The molecule files · Dispatch 001
Six molecules, what each one actually does, the dose we use, and where the evidence stops. No miracle claims — if we cannot say it plainly, it is not in here.
Copper tripeptide-1 · facial serum
GHK is a three-amino-acid peptide — glycine, histidine, lysine — that occurs naturally in human plasma and binds copper with high affinity. Plasma levels are high in youth and fall steeply with age. That decline is the entire reason this molecule is interesting.
Your skin already knows this molecule. It simply has less of it than it used to.
Applied topically, GHK-Cu acts as a signal rather than an ingredient: it has been shown in laboratory and human skin studies to support collagen and elastin synthesis, encourage the skin's own remodeling processes, and act as an antioxidant. It does not sit on the surface pretending to be collagen — it asks the skin to make its own.
| Molecule | Copper tripeptide-1 · GHK-Cu |
| Form | Aqueous serum, 1 fl oz [30 ml] amber dropper |
| Why this form | Copper peptides are water-soluble and best delivered leave-on to bare skin, before heavier occlusives |
| Ritual | Morning or evening, on clean damp skin, before moisturizer |
| Honest timeline | Skin renewal is a cellular process — expect 4–8 weeks of consistency before you judge it |
Most GHK-Cu research is laboratory work, small human studies, or in-vitro skin models — not large randomized trials. It supports the skin's renewal machinery; it does not erase wrinkles, and no serum does. Copper peptides and direct-acid or strong vitamin C routines can destabilize each other — space them, do not layer them.
Nicotinamide adenine dinucleotide · 300 mg/ml intranasal
NAD+ is a coenzyme present in every cell you own. It is the currency your mitochondria use to turn fuel into energy, and it is required by the enzymes that carry out DNA repair and cellular housekeeping. Levels fall with age. That is not a marketing line — it is one of the better-established observations in cell biology.
The hard part has never been the molecule. It has been getting it anywhere useful.
Swallowed, most of it never survives the trip. The nose is a shorter road.
NAD+ taken orally is largely broken down in digestion before it reaches circulation, which is why the supplement industry mostly sells precursors instead. Intranasal delivery bypasses the gut entirely, across a thin and well-perfused membrane — a direct route, in a two-second ritual.
| Molecule | NAD+ · 300 mg/ml |
| Form | Metered nasal spray, 15 ml |
| Why this form | Avoids first-pass digestion, which degrades oral NAD+ |
| Ritual | Morning. One metered spray per nostril |
| Contains | NAD+ and carrier. Nothing else. No caffeine, no stimulant |
That NAD+ is central to cellular energy is settled science. That supplementing it reverses aging is not — human trials are early, small, and mostly on precursors rather than NAD+ itself, and long-term intranasal data is limited. Intranasal delivery of NAD+ is not an FDA-approved route. We sell it because the mechanism is sound and the delivery is honest, not because we can promise you an outcome.
Reduced L-glutathione · facial mist
Glutathione is the antioxidant your own cells manufacture — a tripeptide of glutamate, cysteine and glycine, often called the master antioxidant because it regenerates other antioxidants after they have done their work. Its job is to neutralize oxidative stress: the daily chemistry of sun, pollution and city air that dulls skin before its time.
We put it in a mist rather than a capsule for the same reason we put NAD+ in a nose: delivery decides everything. Applied where the day actually lands — on the face — it does its work at the point of contact.
| Molecule | Reduced L-glutathione |
| Form | Fine-mist facial spray, 30 ml frosted glass |
| Why this form | Topical application at the site of oxidative exposure; oral glutathione is poorly absorbed intact |
| Ritual | Morning, over clean skin, before or after serum. Re-mist after sun or a long day out |
Glutathione's antioxidant chemistry is not in question. Its use as a skin-brightening agent is popular and widely marketed, but topical human evidence is modest and inconsistent, and injectable glutathione for skin lightening is explicitly not something we endorse or sell. This is antioxidant support, not a bleaching product, and we will not describe it as one.
Methylthioninium chloride · 25 mg capsule
Methylene blue is one of the oldest synthetic molecules in medicine — first made in 1876, used as a dye, then as an antimalarial, and still used clinically today. Its second life is cellular: at low doses it can act as an alternative electron carrier in the mitochondrial electron transport chain, the literal engine that turns oxygen and fuel into usable energy.
Focus without a stimulant. No caffeine, no crash, no borrowed tomorrow.
That mechanism is why it draws interest for cognition and cellular energy. It is also why dose discipline matters more here than anywhere else in the house: methylene blue's effects are hormetic — low doses behave differently from high ones.
| Molecule | Methylthioninium chloride · pharmaceutical grade |
| Dose | 25 mg per capsule · 60 capsules |
| Why this dose | Low-dose range, where the electron-carrier behavior is described. More is not better with this molecule |
| Ritual | Morning, with food |
| Expect | Blue-green urine. Harmless, and a reliable sign it is the real thing |
Human cognitive evidence is preliminary. More importantly: methylene blue interacts dangerously with serotonergic medications — SSRIs, SNRIs, MAOIs and others — with a real risk of serotonin syndrome. If you take an antidepressant, do not take this molecule without a physician. It is also inappropriate in G6PD deficiency and in pregnancy. This is the one product in the house where we would rather you talk to our doctor first.
BPC-157 · KPV · TB-500 · larazotide — 500 mcg each
Four peptides that share one neighborhood: the lining of the gut. BPC-157 is a synthetic fragment derived from a protein found in gastric juice, studied for tissue repair. KPV is a tripeptide fragment of alpha-MSH with anti-inflammatory activity in the gut in preclinical work. TB-500 is a synthetic form of a thymosin beta-4 fragment, studied for tissue remodeling. Larazotide is the outlier and the most clinically advanced of the four — it has been through human trials as a tight-junction regulator, the protein gates that decide what the gut lets through.
We print all four names and all four doses. Nobody in this category is required to, which is precisely why we do.
| Molecules | BPC-157 · KPV · TB-500 · larazotide |
| Dose | 500 mcg each per capsule · 60 capsules |
| Form | Oral capsule — the target tissue is the gut itself, so oral is the destination, not a compromise |
| Ritual | Daily, away from food |
Be clear-eyed about this file. BPC-157, KPV and TB-500 evidence is overwhelmingly preclinical — animal and cell models, not large human trials — and BPC-157 is prohibited in competitive sport under WADA. Larazotide has human trial data but has not been approved as a drug. None of these are approved treatments for any gut condition, and none of them replace a gastroenterologist. If you have a diagnosed gut disease, that is a doctor conversation, and we have doctors.
The cognition molecules
Three peptides with three different jobs. Selank is a synthetic analog of tuftsin, a peptide your immune system already makes, studied in Russia for anxiety without sedation — calm that does not cost you your edge. Semax is a synthetic fragment related to ACTH, studied for attention and cognitive performance. Dihexa is a small molecule derived from angiotensin IV research, of interest for its effects on synaptic connections.
Settled, not sedated. That distinction is the whole point of this file.
These arrive together in the Cognition Stack at printed microgram doses — Dihexa 2 mg, Selank 0.3 mg, Semax 0.3 mg, NAD+ 100 mg per capsule — because that is what the label owes you.
| Molecules | Dihexa 2 mg · Selank 0.3 mg · Semax 0.3 mg · NAD+ 100 mg |
| Form | Capsule · 60 count |
| Ritual | Morning, before deep work |
Selank and Semax have clinical history in Russia but are not approved in the United States, and Western trial data is thin. Dihexa is early-stage research material with essentially no human trial evidence — we say that plainly rather than dressing it up. These are not approved treatments for anxiety, ADHD, or any cognitive condition. If you are treating a diagnosed condition, treat it with a physician.
Every file in this dossier ends the same way: with the limit. That is not modesty, it is the product. A brand that only tells you where the science works is not telling you about the science — it is selling you a mood.
— ALT/
This dossier is educational and is not medical advice. Statements have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure, or prevent any disease. Label strengths are first-run targets and may be finalized before release. Consult a licensed physician before beginning any new molecule, particularly if you take prescription medication, are pregnant or nursing, or have a diagnosed condition.
